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Recent research has discovered that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a very particular mutation that creates them more likely to benefit from naltrexone, in comparison with about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director from the UCLA Addictions Laboratory. The findings are available online ( within the journal Neuropsychopharmacology and you will be published in a upcoming print edition with the journal. Using two separate drugs to lose weight naturally can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you need to err to the side of caution and let the FDA do its job and demand some investigation be done so your public recognizes the side effects and hazards of the medications before we drive them. Keep in mind that drug companies have been in business to generate money and that they would say everything to keep people on their own medications. Researchers discovered that participants taking this drug for the year, dropped a few pounds within one month and have kept the extra weight off through the 56 weeks with the study. Contrave is often a combination from the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs which are made up of many active ingredient, which can make them far better and safer. Combo-pilling will be the newest fad or even better the newest in the future under scrutiny and so it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular will be the fact that at the time of right now there are not any long term prescription diet pills that have been authorized by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug could also raise blood pressure level and heart rate, and must not be used in people who have a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure level and heart rate and must 't be used in patients with uncontrolled high blood pressure levels, as well as by you aren't heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients on the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation. 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